![]() ![]() With an average eight blood-clot cases per million in the UK, the risk of blood clots from the AstraZeneca vaccine is much lower than the risks of blood clot from an oral contraceptive pill ( 400 per million in Australia), pregnancy ( 2000 per million) or severe COVID-19 itself (about 31% of people admitted to the ICU, or 310,000 per million ). For the following examples, assume that the UK stats are broadly reflective of vaccine-related blood clots. Numbers can feel very big if they’re compared to numbers we’re familiar with. Note: The following numbers in this article were updated on April 22 2021. Ultimately, such findings have led to the European Medical Agency recommending that the risk of COVID-19 is greater than the risk of AstraZeneca vaccine side-effects. “Many of these individuals are young and have no pre-existing medical conditions, indicating that even relatively healthy individuals may face long-term impacts from their illness.” “Our study is unique in characterising a group consisting of mostly outpatients: 90% of our cohort experienced only a mild COVID-19 illness, yet one-third continue to have lingering effects. “To our knowledge, this study presents the longest follow-up symptom assessment post-illness, with individuals surveyed out to 9 months after their COVID diagnosis,” she told MedPage Today. ![]() “The effects of COVID-19 can linger far beyond acute infection, even in individuals who experienced mild illness,” said author Denise McCulloch of University of Washington. ![]() However, this doesn’t reflect an average population, because the first people to receive first-stage vaccinations were healthcare workers, most of whom are women. Likewise, inititally women under the age of 60 appeared to make up the largest portion of cases in Germany, because 29 of the 31 cases were women in the early days. However, we need to bare in mind that vaccination is still only readily available to the eldery, medical staff and some vulnerable groups, and is not reflective of a normal population The median age of linked cases in Australia was 66, which makes it sound like the side-effects are more common in the elderly. All but one of these are recovering and stable. The most common time for onset was 14 days following administration, but had a range of 2-44 days. Results of blood tests for the D-dimer protein produced by the body to break down clots and anti-PF4 antibodies that activate platelets.īy May 20, the most common clot types were deep vein thrombosis and portal vein thrombosis.Thrombocytopenia (blood platelet count below a certain threshold).In Australia, three criteria must be observed soon after an AstraZeneca administration, for the clot to be consisered linked to the vaccine: “But now there’s more choice and we need to evaluate the data and make a halftime adjustment.”įor some, the decision to mix and match the booster may be driven by concerns about very rare but serious side effects tied to each vaccine: The Johnson & Johnson vaccine has been linked to a very slight increased risk of blood clots in women under 50, and the Pfizer and the Moderna vaccines have been linked to an increased risk of a heart condition called myocarditis, particularly for males under 30.The causal links between AstraZeneca and the blood clotting side effects are still under investigation, and there currently aren’t hard stats about which demographics are most likely to be affected. “When the vaccines were first introduced, the Johnson & Johnson shot did have its benefits and there wasn’t as much supply, so people needed to get whichever vaccine was available,” Sobhanie said. People who chose Johnson & Johnson’s single-dose vaccine out of convenience or people in transient populations who could not commit to a second dose may now be opting for an mRNA booster since the benefits can be delivered in just one booster shot. (The Pfizer and the Moderna vaccines were the first ever authorized using mRNA.) Those who were originally wary of the mRNA technology early on may also be ready to adopt it now, Limaye said.
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